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Patients with mild to moderate renal impairment generally do not require dose adjustment, but closer monitoring may be warranted, particularly for signs of gastrointestinal adverse effects that could lead to dehydration and worsening renal function

Despite widespread adoption, these agents are not approved by the U.S

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Patients commonly report mild anxiety during the patch test, despite no actual reaction, because the experience is unlike anything in their normal skincare routine

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Numbness and tingling in hands and feet Poor balance Poor memory and dementia Mouth or tongue soreness Depression Deficiency is primarily due to issues of malabsorption, poor dietary intake and pernicious anemia